In the late 1950s, Prohias was the president of the Association of Cuban Cartoonists and, when Castro came to power, enjoyed lampooning him in newspaper comics.
In 1960, when he realized that wasn’t a great career move, Prohias fled to the U.S. He was hired by Mad magazine, where he created the popular “Spy vs. Spy” series, drawing the brilliant wordless strips until he retired in 1990. He died from cancer February 24 at age 77.